Baraibar CB, Broncano FJ, Lazaro-Carrasco MJ, and et al. The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Warfarin (Coumadin) interacts with STINGING NETTLE. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. A comprehensive review on nettle effect and efficacy profiles, Part I: herba urticae. www.drweil.com. Planta Med 1997;63:529-32. Medications that cause sleepiness are called sedatives. There are no guidelines for the appropriate use of stinging needle supplements. Stinging nettle contains vitamin K and so could interfere with the anticoagulant drug, warfarin (Coumadin). In fact, one reason to consider effective natural therapies such as stinging nettle and saw palmetto is that popular BPH drugs can cause erectile dysfunction and other negative side effects, while the natural supplements do not. J R Soc Med 2000;93:305-9. More M, Gruenwald J, Pohl U, Uebelhack R. A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study. View abstract. Coming to the stinging nettle plant, you can brew tea from the dried leaves and flowers. Huber, R., Bross, F., Schempp, C., and Grundemann, C. Arnica and stinging nettle for treating burns - a self-experiment. Also, 3.3 grams of stinging nettle leaf has been taken three times daily for 8 weeks. Make a good strong tea from the leaves and allow it to cool completely. View abstract. World J Urol 2005;23:139-46. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. While generally regarded as safe, stinging nettle can cause side effects including mild stomach upset, fluid retention, sweating, diarrhea, and hives or an allergic rash (mainly from topical use). Stinging nettle is a plant in the genus Urtica that originated as a native shrub in colder regions of Europe and Asia and is now found worldwide. All rights reserved. Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Lab. World J Urol. View abstract. Be sure to have your blood checked regularly. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. The dose of your warfarin (Coumadin) might need to be changed. Drink 1 … Cabeza M, Bratoeff E, Heuze I, et al. Stinging nettle above ground parts seem to decrease blood pressure. Never apply stinging nettle to an open wound. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. 2012;69(1):33-39. Stinging nettle products come in dried or freeze-dried leaf form, extract, capsules, tablets, as well as a root tincture (suspension of the herb in alcohol), juice or tea. [Toxicity study of Urtica dioica L. nettle's] . There are no recommendations for correct dosage of stinging nettle for increasing testosterone. Balzarini, J., Neyts, J., Schols, D., Hosoya, M., Van Damme, E., Peumans, W., and De Clercq, E. The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro. Pregnant women should avoid stinging nettle because its hormonal effects could lead to miscarriage. View abstract. Arthritis Res.Ther. View abstract. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. You can stop the treatment as soon as the inflammation has gone down. As for testosterone, this human-based study showed no difference in testosterone levels before, during, or after. Int.Urol.Nephrol. Clin. Phytomedicine 1996;3(2):121-128. For inflammation: When the inflammation begins, drink a few glasses of stinging nettle tea throughout the day. Alt Med Rev 1998;3:140-3. View abstract. Hartmann RW, Mark M, and Soldati F. Inhibition of a 5 a-reductase and aromatase by PHL-00801 (Prostatonin®), a combination of PY102 (Pygeum africanum) and UR 102 (Urtica dioica) extracts. Koch, E. Extracts from Fruits of Saw Palmetto (Sabal serrulata) and Roots of Stinging Nettle (Urtica dioica): Viable Alternatives in the Medical Treatment of Benign Prostatic Hyperplasia and Associated Lower Urinary Tracts Symptoms. © 2005 - 2019 WebMD LLC. Enlarged prostate (benign prostatic hyperplasia or BPH). Klingelhoefer, S., Obertreis, B., Quast, S., and Behnke, B. Antirheumatic effect of IDS 23, a stinging nettle leaf extract, on in vitro expression of T helper cytokines. View abstract. Monitor your blood sugar closely. 1999;26(12):2517-2522. May Reduce Inflammation. 13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Krystofova O, Adam V, Babula P, et al. Read here to find out who is affected by these nettle tea side effects and how to mitigate them. The dose of your diabetes medication might need to be changed. Rough, scaly skin on the scalp and face (seborrheic dermatitis). Stinging nettle can also have a diuretic effect, thereby increasing urinary frequency. View abstract. View abstract. 2005;5(4):1-11. Taking stinging nettle leaf preparations by mouth might also reduce the need for pain medications. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots. View abstract. There is currently no recommended dosage for stinging nettle, but if you are taking it for a specific condition like BPH, then it is advised to take 360 milligrams of root extract per day. Available Forms of Nettle Urtica. Chrubasik, J. E., Roufogalis, B. D., Wagner, H., and Chrubasik, S. A comprehensive review on the stinging nettle effect and efficacy profiles. Some research shows that taking stinging nettle daily for 2-12 months improves urinary tract symptoms and the flow of urine in people with BPH. Bombardelli E and Morazzoni P. Urtica dioica L. Fitoterapia 1997;68(5):387-402. 6. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. Other products containing stinging nettle root extract or a combination of stinging nettle root, saw palmetto lipoidal extract, pumpkin seed oil, lemon bioflavonoid, and beta-carotene don't seem to improve most BPH symptoms. 1998;61(1):119-21. [Urination disorders caused by prostatic hyperplasia. Nettle is possibly effective for the listed uses. Dosage and parts used vary according to the condition being treated. 1988;119(2):269-270. The other parts of the plant can be put into soups and dishes. MMW.Munch.Med Wochenschr. Nutritive tonic- restores the body and adds nutrients. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Mol.Pharmacol. Stinging nettle root has been shown to prevent the conversion of testosterone into dihydrotestosterone (DHT), which will significantly increase the amount of free testosterone in your body… if you’re a rat. Diabetes medications are also used to lower blood sugar. 2. It is still not clear why stinging nettle reduces BPH symptoms, but it is possible that it may affect testosterone and estrogen or act directly on the prostate. Arthritis Res.Ther. Van der Weijden, G. A., Timmer, C. J., Timmerman, M. F., Reijerse, E., Mantel, M. S., and van, der, V. The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis. Marks L, Partin AW, Epstein JI, et al. Quality and active ingredients in supplements may vary widely from maker to maker. Touching the nettle plant can lead to an allergic rash. Stinging Nettle Side Effects ©Copyright 2020 Healthy Lifestyle Brands, LLC. There is conflicting evidence about the effects of stinging nettle on symptoms of BPH. But symptom improvement may depend on the specific stinging nettle product used. Christensen, R. and Bliddal, H. Is Phytalgic(R) a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? Kassen A, Berges R, Senge T, et al. BJU Int 2000;86:439-42. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. By helping the blood clot, stinging nettle might decrease the effectiveness of warfarin (Coumadin). J Rheumatol. Nettle side effects. View abstract. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). View abstract. Stinging nettle capsules are usually offered in 300-milligram to 900-milligram formulations and are generally considered safe at these doses. But it's not known if this benefit of this product is due to stinging nettle, saw palmetto, or both ingredients. 4 g whole herb steeped 10 minutes hot water, three to four times daily. Planta Med 1990;56:44-7. Early research suggests that using stinging nettle above ground parts at the first signs of hay fever symptoms may help provide relief. Clin Exp Obstet Gynecol 2013;40(1):141-143. Because stinging nettle may affect blood sugar, it could interfere with the management of diabetes. Lopatkin, N. A., Sivkov, A. V., Medvedev, A. View abstract. Cancer Biol Ther 2004;3:855-7. View abstract. It gets its name from the fine hairs on its leaves and stems that release … Planta Med 1997;63:307-10. . Engelmann U, Boos G, and Kres H. [Therapy of benign prostatic hyperplasia with Bazoton liquidum]. SOURCES: Optimal doses of stinging nettle have not been set for any condition. Nettle is a powerful plant, which in high doses, can cause multiple issues. View abstract. Stinging nettle root appears to have different pharmacological effects than the leaves. Onal S, Timur S, Okutucu B, Zihnioglu F. Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. (check all that apply). Riehemann, K., Behnke, B., and Schulze-Osthoff, K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kB. CONDITIONS OF USE AND IMPORTANT INFORMATION: Nettle root extract, derived from the stinging nettle plant, is a popular supplement for body builders, and considered a relatively safe supplement as well. Studies indicate that the leaves can relieve joint pain when applied to painful areas of the skin. Pavone, C., Abbadessa, D., Tarantino, M. L., Oxenius, I., Lagana, A., Lupo, A., and Rinella, M. [Associating Serenoa repens, Urtica dioica and Pinus pinaster. Most products on the market give you 500 mg per capsule. Wagner H, Geiger WN, Boos G, and et al. The effect of stinging nettle on A1c in people with diabetes is unclear. Sokeland J. Information from this source is evidence-based and objective, and without commercial influence. Liebigs Ann Chem 1991;335-339. Risks and Side Effects of Stinging Nettle Fortschr Med 1995;113(3):37-40. Pak.J.Biol.Sci. Int J Basic Sci Med. Urologiia. Schneider H, Honold E, and Masuhr T. Treatment of benign prostatic hyperplasia with a combination plant preparation. Adult. Kraus R, Spiteller G, and Bartsch W. [(10E,12Z)-9-Hydroxy-10,12-octadecadienoic acid, an aromatase inhibitor from roots of Urtica dioica]. This could increase how much lithium is in the body and result in serious side effects. Reviewed by Russell Greenfield, M.D., August, 2016. Early research suggests that taking a stinging nettle root preparation for about 4 months is not more effective than standard therapy for improving menstrual cycle conditions, oily skin, or acne in women with high testosterone levels. View abstract. Medications for diabetes (Antidiabetes drugs) interacts with STINGING NETTLE. Farzami B, Ahmadvand D, Vardasbi S, Majin FJ, Khaghani Sh. But overall, nettle is regarded as safe and well-tolerated, with very low risk for side effects or toxicity. Francois, K. O., Auwerx, J., Schols, D., and Balzarini, J. Effect of beta-sitosterol as inhibitor of 5 alpha-reductase in hamster prostate. Complement Ther.Med. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. 2007;39(4):1137-1146. Research studies of stinging nettle typically do not report dosages Stinging nettle root supplements typically supply 500-750 mg dosages Multi-ingredient formulas typically provide smaller dosages (360 mg) Schneider, T. and Rubben, H. [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). Pharmazie. Stinging nettle may lead to minor side effects such as an upset stomach and sweating. View abstract. Reproduction in whole or in part without permission is prohibited. FEBS Lett 1-8-1999;442(1):89-94. Use caution if you have low blood pressure. Int J Environ Res Public Health. Randall C, Randall H, Dobbs F, et al. University of Maryland Medical Center. Anti-allergic– reduces allergic symptoms via mast cell stabilization. Consumerlab. 2017 Oct;22(4):603-608. For treating arthritis, one study had success using fresh nettle leaves to "sting" the arthritic joint once daily.For allergy treatment, a dose of 300 mg of stinging nettle extract three times a day is sometimes suggested.For treating an enlarged prostate, studies have used various doses, such as 80 mg three times daily or 120 mg twice daily (in combination with other herbs). Safety and efficacy in the treatment of lower urinary tract symptoms. Stinging nettle might have an effect like a water pill or "diuretic." J Contemp Dent Pract 2010;11(1):E088-E094. Mills S, Bone K. Principles and Practice of Phytotherapy. Nettle is available under the following different brand and other names: stinging nettle, and Urtica dioica. 2008;15(4):236-237. The urticaria is accompanied by a stinging sensation lasting longer than 12 h. There 2010;12(1):105. Edgcumbe, D. P. and McAuley, D. Hypoglycaemia related to ingestion of a herbal remedy. View abstract. View abstract. View abstract. Planta Med 2000;66:44-7. Topical ointments and creams that contain stinging nettle are also available. Medscape - Indication-specific dosing for stinging nettle, urtica dioica (nettle), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & … [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]. Many studies have evaluated a particular combination product that contains stinging nettle and saw palmetto (PRO 160/120 by Willmar Schwabe GmbH). View abstract. Nettle leaf extract is traditionally available in the form of dried or frozen leaves, creams, ointments and pills. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Freeze-dried stinging nettle may help relieve the symptoms of hay fever and other allergies.